Google said protesters were disrupting offices and were “physically impeding other employees’ work and preventing them from accessing facilities”.
The dismissals, which Google confirmed to the BBC, escalated longstanding tensions between the company and employees opposed to supplying technology to Israel’s government.
Marches were held last year, following the start of the war in Gaza in October, with protesters holding banners that read “No More Genocide For Profit”.
In the most recent protests, staff entered offices and refused to leave prompting Google to call law enforcement.
In a statement Google called the behaviour “completely unacceptable”.