A section of the M1 motorway has been closed in both directions following a serious collision.
The crash was reported shortly before 07:00 BST on Sunday.
Belfast-bound traffic is being diverted at junction six, Saintfield Road.
There is a diversion in place for Lisburn-bound traffic at junction three, Blacks Road.
Police say the M1 is likely to be closed for some time and motorists are advised to take an alternative route.