{"id":36191,"date":"2024-06-10T04:43:01","date_gmt":"2024-06-10T04:43:01","guid":{"rendered":"https:\/\/kede.com.br\/news\/antidepressant-withdrawal-affects-one-in-six-people\/"},"modified":"2024-06-10T04:43:03","modified_gmt":"2024-06-10T04:43:03","slug":"antidepressant-withdrawal-affects-one-in-six-people","status":"publish","type":"post","link":"https:\/\/kede.com.br\/news\/antidepressant-withdrawal-affects-one-in-six-people\/","title":{"rendered":"Antidepressant withdrawal affects one in six people"},"content":{"rendered":"<p> <br \/>\n<\/p>\n<div id=\"\">\n<div data-component=\"byline-block\" class=\"sc-43e6b7ba-0 bWSguZ\">\n<div data-testid=\"byline\" class=\"sc-1d2e900b-0 fhxEhT\">\n<div class=\"sc-1d2e900b-1 gwgaEc\">\n<p><time class=\"sc-1d2e900b-10 WPunI\">4 days ago<\/time><\/p>\n<div class=\"sc-1d2e900b-2 bDFePy\">\n<p><span data-testid=\"byline-name\" class=\"sc-1d2e900b-6 hhBctz\">By\u00a0<!-- -->Philippa Roxby<!-- -->,\u00a0<!-- --><\/span><span class=\"sc-1d2e900b-7 jbvpvO\">Health reporter, BBC News<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<figure>\n<div data-component=\"image-block\" class=\"sc-43e6b7ba-0 dWCXVg\">\n<div data-testid=\"hero-image\" class=\"sc-13b8515c-1 bbjeKz\"><img sizes=\"(min-width: 1280px) 50vw, (min-width: 1008px) 66vw, 96vw\" srcset=\"https:\/\/ichef.bbci.co.uk\/news\/240\/cpsprodpb\/12bf\/live\/247cd290-23ce-11ef-85e1-b5cf8721ba30.jpg.webp 240w,https:\/\/ichef.bbci.co.uk\/news\/320\/cpsprodpb\/12bf\/live\/247cd290-23ce-11ef-85e1-b5cf8721ba30.jpg.webp 320w,https:\/\/ichef.bbci.co.uk\/news\/480\/cpsprodpb\/12bf\/live\/247cd290-23ce-11ef-85e1-b5cf8721ba30.jpg.webp 480w,https:\/\/ichef.bbci.co.uk\/news\/640\/cpsprodpb\/12bf\/live\/247cd290-23ce-11ef-85e1-b5cf8721ba30.jpg.webp 640w,https:\/\/ichef.bbci.co.uk\/news\/800\/cpsprodpb\/12bf\/live\/247cd290-23ce-11ef-85e1-b5cf8721ba30.jpg.webp 800w,https:\/\/ichef.bbci.co.uk\/news\/1024\/cpsprodpb\/12bf\/live\/247cd290-23ce-11ef-85e1-b5cf8721ba30.jpg.webp 1024w,https:\/\/ichef.bbci.co.uk\/news\/1536\/cpsprodpb\/12bf\/live\/247cd290-23ce-11ef-85e1-b5cf8721ba30.jpg.webp 1536w\" src=\"https:\/\/ichef.bbci.co.uk\/news\/480\/cpsprodpb\/12bf\/live\/247cd290-23ce-11ef-85e1-b5cf8721ba30.jpg.webp\" loading=\"eager\" alt=\"Getty Images Woman taking antidepressant\" class=\"sc-13b8515c-0 hbOWRP\"\/><span class=\"sc-13b8515c-2 iuvLSH\">Getty Images<\/span><\/div>\n<\/div>\n<\/figure>\n<div data-component=\"text-block\" class=\"sc-43e6b7ba-0 bWSguZ\">\n<p class=\"sc-eb7bd5f6-0 fYAfXe\">One out of every six people have symptoms when they stop taking antidepressants &#8211; fewer than previously thought, a review of previous studies suggests.<!-- --><\/p>\n<p class=\"sc-eb7bd5f6-0 fYAfXe\">The researchers say their findings will help inform doctors and patients &#8220;without causing undue alarm&#8221;.<!-- --><\/p>\n<p class=\"sc-eb7bd5f6-0 fYAfXe\">The Lancet Psychiatry review looked at data from 79 trials involving more than 20,000 patients.<!-- --><\/p>\n<p class=\"sc-eb7bd5f6-0 fYAfXe\">Some had been treated with antidepressants and others with a dummy drug or placebo, which helped researchers gauge the true effect of withdrawing from the drugs.<!-- --><\/p>\n<\/div>\n<div data-component=\"text-block\" class=\"sc-43e6b7ba-0 bWSguZ\">\n<p class=\"sc-eb7bd5f6-0 fYAfXe\">Some people have unpleasant symptoms such as dizziness, headache, nausea and insomnia when they stop taking antidepressants, which, the researchers say, can cause considerable distress.<!-- --><\/p>\n<p class=\"sc-eb7bd5f6-0 fYAfXe\">Previous estimates suggested antidepressant discontinuation symptoms (ADS) affected 56% of patients, with almost half of cases classed as severe.<!-- --><\/p>\n<p class=\"sc-eb7bd5f6-0 fYAfXe\">But this review, from the Universities of Berlin and Cologne, estimates:<!-- --><\/p>\n<ul class=\"sc-5c9c90b0-0 cnfHHs\">\n<li class=\"sc-8d73edac-0 ezcCTE\">One out of every every six or seven patients can expect symptoms when stopping antidepressants<!-- --><\/li>\n<li class=\"sc-8d73edac-0 ezcCTE\">One in 35 will have severe symptoms<!-- --><\/li>\n<li class=\"sc-8d73edac-0 ezcCTE\">Symptoms are more common with some antidepressants than others<!-- --><\/li>\n<\/ul>\n<p class=\"sc-eb7bd5f6-0 fYAfXe\"><a target=\"_blank\" href=\"https:\/\/www.nice.org.uk\/guidance\/ng222\/chapter\/Recommendations\" class=\"sc-c9299ecf-0 bZUiKB\" rel=\"noopener\">Official health guidance<!-- --><\/a> is to reduce the dose of antidepressant medication in stages over time, rather than stopping it suddenly or missing doses, which could lead to withdrawal symptoms.<!-- --><\/p>\n<p class=\"sc-eb7bd5f6-0 fYAfXe\">Most people stop antidepressants successfully, the guidance adds.<!-- --><\/p>\n<p class=\"sc-eb7bd5f6-0 fYAfXe\">Other research suggests ADS lasts for one to two weeks.<!-- --><\/p>\n<p class=\"sc-eb7bd5f6-0 fYAfXe\">Study author Prof Christopher Baethge, from the department of psychiatry and psychotherapy, at the University of Cologne, said the findings were &#8220;quite robust&#8221;.<!-- --><\/p>\n<p class=\"sc-eb7bd5f6-0 fYAfXe\">But the review&#8217;s lower estimate of ADS &#8220;did not mean it&#8217;s all in their heads&#8221;.<!-- --><\/p>\n<\/div>\n<p><h2 class=\"sc-518485e5-0 kRvAla\">&#8216;Worsening anxiety&#8217;<!-- --><\/h2>\n<\/p>\n<div data-component=\"text-block\" class=\"sc-43e6b7ba-0 bWSguZ\">\n<p class=\"sc-eb7bd5f6-0 fYAfXe\">It found 17% of people experienced symptoms after stopping a placebo or dummy drug.<!-- --><\/p>\n<p class=\"sc-eb7bd5f6-0 fYAfXe\">&#8220;A possible explanation is greater awareness of worsening anxiety and depression after stopping a seemingly helpful medication,&#8221; Prof Baethge said.<!-- --><\/p>\n<p class=\"sc-eb7bd5f6-0 fYAfXe\">Many of the 40 symptoms linked to stopping antidepressants can also be caused by other ailments.<!-- --><\/p>\n<p class=\"sc-eb7bd5f6-0 fYAfXe\">&#8220;It shows the importance of comparing antidepressants with placebo when studying  discontinuation,&#8221; said Prof Glyn Lewis, from University College London. <!-- --><\/p>\n<p class=\"sc-eb7bd5f6-0 fYAfXe\">The most commonly used antidepressants in the UK &#8211; citalopram, sertraline and fluoxetine &#8211; had the lowest risk of ADS.<!-- --><\/p>\n<p class=\"sc-eb7bd5f6-0 fYAfXe\">But venlafaxine, which is also used in the UK, had the second highest.<!-- --><\/p>\n<\/div>\n<p><h2 class=\"sc-518485e5-0 kRvAla\">&#8216;High risk&#8217;<!-- --><\/h2>\n<\/p>\n<div data-component=\"text-block\" class=\"sc-43e6b7ba-0 bWSguZ\">\n<p class=\"sc-eb7bd5f6-0 fYAfXe\">Consultant psychiatrist and fellow of the Royal College of Psychiatrists Dr Paul Keedwell said people planning to stop their medication should always seek medical advice. <!-- --><\/p>\n<p class=\"sc-eb7bd5f6-0 fYAfXe\">\u201cFirstly, depending on your mental-health history, there might be a high risk of relapse of your depression,&#8221; he said. <!-- --><\/p>\n<p class=\"sc-eb7bd5f6-0 fYAfXe\">&#8220;Sometimes a relapse of depression can be confused with withdrawal symptoms.<!-- --><\/p>\n<p class=\"sc-eb7bd5f6-0 fYAfXe\">\u201cSecondly, unpleasant withdrawal symptoms can be largely prevented with proper medical supervision.<!-- --><\/p>\n<p class=\"sc-eb7bd5f6-0 fYAfXe\">&#8220;It is important to say that withdrawal symptoms are not dangerous and the risk of experiencing them at some future date should not be a reason for refusing antidepressant treatment. <!-- --><\/p>\n<p class=\"sc-eb7bd5f6-0 fYAfXe\">&#8220;The pros and cons of treatment should always be discussed with your doctor.\u201d<!-- --><\/p>\n<p class=\"sc-eb7bd5f6-0 fYAfXe\">More than eight million people in England are taking antidepressants, for depression, anxiety, obsessive-compulsive disorder and other conditions &#8211; a million more than five years ago.<!-- --><\/p>\n<\/div>\n<\/div>\n<p><br \/>\n<br \/><a href=\"https:\/\/www.bbc.com\/news\/articles\/c3ggv7zvzw3o\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>4 days ago By\u00a0Philippa Roxby,\u00a0Health reporter, BBC News Getty Images One out of every six people have symptoms when they stop taking antidepressants &#8211; fewer than previously thought, a review of previous studies suggests. The researchers say their findings will help inform doctors and patients &#8220;without causing undue alarm&#8221;. The Lancet Psychiatry review looked at [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":36192,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[64],"tags":[8173,13837,70,13838],"_links":{"self":[{"href":"https:\/\/kede.com.br\/news\/wp-json\/wp\/v2\/posts\/36191"}],"collection":[{"href":"https:\/\/kede.com.br\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kede.com.br\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kede.com.br\/news\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/kede.com.br\/news\/wp-json\/wp\/v2\/comments?post=36191"}],"version-history":[{"count":1,"href":"https:\/\/kede.com.br\/news\/wp-json\/wp\/v2\/posts\/36191\/revisions"}],"predecessor-version":[{"id":36193,"href":"https:\/\/kede.com.br\/news\/wp-json\/wp\/v2\/posts\/36191\/revisions\/36193"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/kede.com.br\/news\/wp-json\/wp\/v2\/media\/36192"}],"wp:attachment":[{"href":"https:\/\/kede.com.br\/news\/wp-json\/wp\/v2\/media?parent=36191"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kede.com.br\/news\/wp-json\/wp\/v2\/categories?post=36191"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kede.com.br\/news\/wp-json\/wp\/v2\/tags?post=36191"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}