{"id":39312,"date":"2024-07-27T06:15:58","date_gmt":"2024-07-27T06:15:58","guid":{"rendered":"https:\/\/kede.com.br\/news\/womans-hands-can-triple-in-size-amid-rare-swelling-attacks\/"},"modified":"2024-07-27T06:15:59","modified_gmt":"2024-07-27T06:15:59","slug":"womans-hands-can-triple-in-size-amid-rare-swelling-attacks","status":"publish","type":"post","link":"https:\/\/kede.com.br\/news\/womans-hands-can-triple-in-size-amid-rare-swelling-attacks\/","title":{"rendered":"Woman’s hands can triple in size amid rare swelling attacks"},"content":{"rendered":"


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\"ChloeChloe Davies<\/span><\/div>\n<\/div>\n

Chloe Davies has hereditary angioedema, which can be life-threatening<\/figcaption><\/p>\n<\/figure>\n
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A woman whose body does not recognise when to stop swelling says a drug trial has been “life-changing”. <\/p>\n

Chloe Davies, 32, who lives in Bristol, has hereditary angioedema (HAE), which causes “spontaneous swelling attacks”. <\/p>\n

“If my hand swelled up it would just keep going and going. Severe attacks can leave me hospitalised and are extremely disruptive to everyday life,” she said. <\/p>\n

She has been taking part in the trial with North Bristol NHS Trust, which has reduced her attacks from one every four to six days to none in more than a year.<\/p>\n<\/div>\n

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The condition, which affects around one in 50,000 people, can be life-threatening if swelling happens in the throat. <\/p>\n

There is no cure, but treatment can be given to help patients manage their condition.<\/p>\n

Ms Davies first began experiencing symptoms as a child, but did not receive a diagnosis until she was 15.<\/p>\n

Initially, it was thought she was experiencing an allergic reaction. <\/p>\n

She remembers experiencing flare-ups where her hands “tripled in size” and the swelling would gradually spread higher up her arm. <\/p>\n<\/div>\n

‘Validating’ diagnosis<\/h2>\n<\/p>\n
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During her childhood, she regularly suffered with “bad” stomach aches and sickness bugs, which would last longer than usual. <\/p>\n

“I remember lying on the sofa being in quite severe pain, but not realising it [was HAE] at that point. <\/p>\n

“No one can see what’s going on internally so they just assumed that I was making a bigger fuss than everyone else,” she said.<\/p>\n

She added that receiving a diagnosis after years of suffering had been “very validating”. <\/p>\n<\/div>\n

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There are different types of angioedema, which vary in severity. <\/p>\n

According to the NHS<\/a>, the condition causes sudden swelling and commonly affects the face, hands and feet. <\/p>\n

Sometimes the bowel can become swollen, leading to stomach pain. <\/p>\n<\/div>\n

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\"ChloeChloe Davies<\/span><\/div>\n<\/div>\n

Ms Davies said the drug trial has been “amazing” <\/figcaption><\/p>\n<\/figure>\n
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Ms Davies’ HAE symptoms became “much worse” after having her daughter nine years ago. <\/p>\n

Her monthly flare-ups began occurring every four days, which “dramatically” impacted her life.<\/p>\n

Every attack required treatment via an intravenous injection. <\/p>\n

“It gave me what I needed to be able to bounce back, but it\u2019s never nice giving yourself an injection,” she said. <\/p>\n

She added the treatment had been “tricky”, particularly when having to administer it while on the go.<\/p>\n<\/div>\n

‘Immediate difference’<\/h2>\n<\/p>\n
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Eighteen months ago, Ms Davies’ consultant – who specialises in HAE – suggested trialling a new medication at Southmead Hospital. <\/p>\n

It involves an injection into the subcutaneous fat under the skin to deliver a drug into the bloodstream. <\/p>\n

The drug works to lower the amount of a protein produced by the liver that causes the swelling.<\/p>\n

Ms Davies was given the real drug, rather than a placebo. <\/p>\n

She noticed an “immediate” difference and has only experienced one flare-up since starting the treatment. <\/p>\n

“It’s amazing – it’s changed my life,” she said. <\/p>\n

“It’s helped provide a space to do what I want without worrying. <\/p>\n

“I feel genuinely very cared for and the research team at North Bristol NHS Trust has been really great.” <\/p>\n

She added: “It’s changed my opinion of doing a trial.”<\/p>\n<\/div>\n<\/div>\n


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Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Chloe Davies Chloe Davies has hereditary angioedema, which can be life-threatening A woman whose body does not recognise when to stop swelling says a drug trial has been “life-changing”. Chloe Davies, 32, who lives in Bristol, has hereditary angioedema (HAE), which causes “spontaneous swelling attacks”. “If my hand swelled up it would just keep going […]<\/p>\n","protected":false},"author":1,"featured_media":39313,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[64],"tags":[6493,3642,4354,14472,14473,5974,2853],"_links":{"self":[{"href":"https:\/\/kede.com.br\/news\/wp-json\/wp\/v2\/posts\/39312"}],"collection":[{"href":"https:\/\/kede.com.br\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kede.com.br\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kede.com.br\/news\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/kede.com.br\/news\/wp-json\/wp\/v2\/comments?post=39312"}],"version-history":[{"count":1,"href":"https:\/\/kede.com.br\/news\/wp-json\/wp\/v2\/posts\/39312\/revisions"}],"predecessor-version":[{"id":39314,"href":"https:\/\/kede.com.br\/news\/wp-json\/wp\/v2\/posts\/39312\/revisions\/39314"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/kede.com.br\/news\/wp-json\/wp\/v2\/media\/39313"}],"wp:attachment":[{"href":"https:\/\/kede.com.br\/news\/wp-json\/wp\/v2\/media?parent=39312"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kede.com.br\/news\/wp-json\/wp\/v2\/categories?post=39312"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kede.com.br\/news\/wp-json\/wp\/v2\/tags?post=39312"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}