Jack Draper’s run at the Cincinnati Open ended in the quarter-finals as he was beaten in straight sets by Denmark’s Holger Rune.

The British number one had come from a set down to win his previous two matches, but the 22-year-old was unable to repeat the feat against the 15th seed.

Rune won 6-4 6-2 after taking his chance on the only break point of the first set, which put him 3-2 up.

The Dane broke again at the start of the second set and saved three break points, seizing his only other opportunity on Draper’s serve in the 11th game before serving out for victory.

Rune, 21, will play Frances Tiafoe in the last four after Hubert Hurkacz retired from their quarter-final because of a calf injury after losing the first set.

Top seed Jannick Sinner of Italy avenged last week’s defeat by Andrey Rublev in Montreal, winning 4-6 7-5 6-4 to set up a semi-final against Alexander Zverev, who beat Ben Shelton 3-6 7-6 7-5.

The women’s world number one Iga Swiatek of Poland beat Mirra Andreeva 4-6 6-3 7-5 and will next face third seed Aryna Sabalenka, who beat Liudmila Samsonova 6-3 6-3.

Home hope Jessica Pegula saw off the challenge of Leylah Fernandez 7-5 6-7 7-6 and will meet Paula Badosa, who cruised to a 6-3 6-2 win against Anastasia Pavlyuchenkova.