Lionel Messi was substituted during Inter Miami’s latest Major League Soccer match because of “muscle fatigue” in his left hamstring, his club said on Monday.

There had been fears that the 2022 World Cup winner had suffered an injury during Inter Miami’s 6-4 win over Philadelphia Union.

However, the MLS club announced that medical tests showed that it was nothing more than “an overload associated with muscle fatigue”.

“The timeline for his return to physical activity will depend on his clinical and functional progress,” Inter Miami said.

Having set up two of Miami’s four first-half goals on Sunday, Messi clutched his leg in the 73rd minute after taking a free-kick and was immediately withdrawn in the team’s final game before the World Cup break.

The 38-year-old went straight down the tunnel but appeared to be walking normally.

“He really was fatigued,” Miami coach Guillermo Hoyos said after the game when asked about Messi’s condition. “He was tired; the pitch was heavy and when in doubt, the standard approach is always to ensure you don’t take any risks.”

Messi has not formally confirmed he plans to play for defending champions Argentina in the World Cup, which begins on 11 June.

However, he is widely expected to make a record-equalling sixth appearance at a World Cup, with the tournament being co-hosted by the United States, Canada and Mexico.

Argentina’s squad is due to be named next week, with their opening game against Algeria on 16 June.

Since moving to Miami in 2023, the Barcelona legend and eight-time Ballon d’Or winner has carefully managed his workload but has still spent spells out of action with hamstring issues.

He has 12 goals and eight assists in 14 MLS games this season, only one behind the leader in each category, having scored a league-leading 29 goals and assisted 19 times in 28 games during the 2025 regular season.